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Medetomidine: What Is It and Why Is It Showing Up in Fentanyl?

The illicit drug supply continues to change, creating new risks for people who use substances and new challenges for healthcare providers. One substance receiving growing attention is medetomidine, a powerful veterinary sedative that is increasingly being detected in the illegal fentanyl supply. In April 2026, the Centers for Disease Control and Prevention (CDC) issued a health advisory warning about increasing medetomidine detections across the United States, particularly in the Northeast.…
Marissa Zinsser
August 20, 2026